Comparison of 3% Mepivacaine and 2% Procaine in Local Anesthetics as Antibacterial Activity on the Growth of Porphyromonas Gingivalis

Harvery, Jessica Grace and Kaiin, Harry Arifin and Sugiaman, Vinna K. (2023) Comparison of 3% Mepivacaine and 2% Procaine in Local Anesthetics as Antibacterial Activity on the Growth of Porphyromonas Gingivalis. JIDMR - Journal of International Dental and Medical Research, 16 (3). pp. 1076-1083. ISSN 1309-100X

	Text 32. JIDMR, 2023_ 16 (3) 1076-1083.pdf Download (1487Kb)
	Text 31. Turnitin-Comparison of 3_ Mepivacaine and 2_ Procaine in Local Anesthetics.pdf Download (2442Kb)

Abstract

In dentistry, local anesthesia is needed, especially for oral and maxillofacial surgery to reduce the sensation of pain. Besides its use as an analgesic, local anesthetics also have antibacterial activity which inhibits the growth of various bacteria. The purpose of this study was to determine the antibacterial activity of procaine and mepivacaine in inhibiting the growth of Porphyromonas gingivalis. In this study, the antibacterial activity test was carried out using the Kirby-Bauer diffusion method for ten repetitions and four treatment groups tested, 2% procaine, 3% mepivacaine, metronidazole as a positive control, and aquadest as a negative control dripped on paper discs and incubated for 24 hours. The results showed that procaine and mepivacaine had antibacterial activity with inhibition zone diameters of 9.36 mm and 8.47 mm, metronidazole 11.80 mm, and aquadest showed no inhibition diameter. The results of the research data were analyzed using the One-way ANOVA test. There was a significant difference in the diameter of the inhibition zone (p <0.05) between the four treatment. Two percent procaine and 3% mepivacaine have antibacterial activity against the growth of Porphyromonas gingivalis which is classified as a moderate inhibitory response according to David and Stout.

Item Type:	Article
Contributors:	Contribution Contributors NIDN/NIDK Email UNSPECIFIED Harvery, Jessica Grace UNSPECIFIED UNSPECIFIED UNSPECIFIED Kaiin, Harry Arifin UNSPECIFIED UNSPECIFIED UNSPECIFIED Sugiaman, Vinna K. UNSPECIFIED UNSPECIFIED
Uncontrolled Keywords:	Antibacterial; Inhibition, Mepivacaine; Porphyromonas gingivalis; Procaine.
Subjects:	R Medicine > R Medicine (General)
Depositing User:	Perpustakaan Maranatha
Date Deposited:	29 Nov 2023 08:44
Last Modified:	10 Dec 2023 17:46
URI:	http://repository.maranatha.edu/id/eprint/32371

Actions (login required)

View Item