Antioxidant Activity and Anticarcinogenic Properties of Combination Extract of Soursop (Annona Muricata Linn) and Pearl Grass (Hedyotis Corymbosa (L.) Lam.)

Endrini, Susi and Suherman, Suherman and Widowati, Wahyu (2015) Antioxidant Activity and Anticarcinogenic Properties of Combination Extract of Soursop (Annona Muricata Linn) and Pearl Grass (Hedyotis Corymbosa (L.) Lam.). Malaysian Journal of Analytical Sciences, 19 (2). pp. 284-290.

[img]
Preview
 Text
9.Int Publikasi 2015-6 (Susi MJAS-Wahyu-FKUKM) Reviewer.pdf
Download (3882Kb) | Preview
[img]
Preview
 Text
Turnitin_Int Publikasi 2015-7 (Susi MJAS-Wahyu-FKUKM).pdf.pdf
Download (1569Kb) | Preview

Abstract

Soursop (Annona muricata) has numerous traditional medicinal uses in South American and the Caribbean, and it has become a popular nutritional medicinal supplement. In the other hand, pearl grass (Hedyotis corymbosa (L.) Lam.) has long been used traditionally as an anti-inflammatory. In this study, soursop and pearl grass combined to obtain extracts that have anticancer effects and anti-inflammatory effects, as most patients with cancer, particularly advanced breast cancer often experience inflammation. Two types of combination of extracts made by different solvents ie ethanol extract combination (CSEPE) and water extract combination (CSWPW) have been used. The anticarcinogenic properties of both extracts have been studied by using MTT assay. The antioxidative activity of the extracts which could contribute to their cytotoxic properties was also studied by using DPPH assay. The results showed that the combination extract of ethanolic extract of soursop and pearl grass (CSEPE) has potential anticarcinogenic properties and the properties was decreased during the increment of incubation time but increased with the increasement of doses. However, the combination extract of water extract of soursop and pearl grass (CSWPW) did not displayed the potential anticarcinogenic properties. The anticarcinogenic properties of CSEPE could be due to their high antioxidant activities.

Item Type: Article
Uncontrolled Keywords: MTT assay, soursop, pearl grass, MCF-7, antioxidant activity, cytotoxic properties
Subjects: R Medicine > R Medicine (General)
Depositing User: Perpustakaan Maranatha
Date Deposited: 06 Oct 2020 05:18
Last Modified: 05 Nov 2021 04:51
URI: http://repository.maranatha.edu/id/eprint/27379

Actions (login required)

View Item View Item
MCUrepository is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.