Effects of Pomegranate Peel (Punica granatum L.) Extract as an Anthelmintic

Amelia, Monica and Jasaputra, Diana Krisanti and Tjokropranoto, Rita (2017) Effects of Pomegranate Peel (Punica granatum L.) Extract as an Anthelmintic. Journal of Medicine and Health, 1 (5). pp. 409-416. ISSN 2442-5257

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Abstract

Helminths infections caused by Soil-Transmitted Helminths (STH) are found in many people living in developing countries, especially in rural areas. People often use pomegranate as an anthelmintic. The aim of this research is to find out the effects of pomegranate peel (Punica granatum L.) as an anthelmintic to female Ascaris suum in vitro. The research on the effects of pomegranate peel extract has been conducted on 900 female Ascaris suum in vitro. Ascaris suum are divided into 5 groups, group I: pomegranate peel extract of dose 25%, group II: pomegranate peel extract of 50%, group III: pomegranate peel extract of 75%, group IV: 0.9% NaCl as a negative control, and group V is given mebendazole 0.5% as a positive control. The mean percentage of dead worms in group I is 39%, in group II 61%, while in group III 82%, but its potential is lower than mebendazole, which kills 100%. The treatment using pomegranate peel extract of 25%, 50% and 75% respectively has significant differences with p < 0.05 against negative control (NC) using a 0.9% NaCl. The research concludes that the pomegranate peel extract has an anthelmintic effect against Ascaris suum females in vitro.

Item Type:	Article
Uncontrolled Keywords:	pomegranate peel extract, anthelmintic effect, in vitro
Subjects:	R Medicine > R Medicine (General)
Depositing User:	Perpustakaan Maranatha
Date Deposited:	17 Apr 2018 06:14
Last Modified:	10 Nov 2021 08:31
URI:	http://repository.maranatha.edu/id/eprint/24356

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