Antibacterial effects of tomato ethanol extract (Solanum lycopersicum L.) against S. mutans and P. gingivalis: a laboratory experiment

Rahmawati, Dicha Yuliadewi and Kurniawan, Viola Febi and Sanjaya, Oei Tirza Cintya and Sugiaman, Vinna Kurniawati (2023) Antibacterial effects of tomato ethanol extract (Solanum lycopersicum L.) against S. mutans and P. gingivalis: a laboratory experiment. Padjadjaran Journal of Dentistry, 35 (3). pp. 230-236. ISSN 2549-6212

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Abstract

Introduction: The process of dental plaque formation consists of three stages: first is the pellicle formation; second is the initial colonization of facultative gram-positive one of microbes of S. mutans; last is secondary colonization and microbial maturation by Porphyromonas intermedia, P. gingivalis, Fusobacterium nucleatum. Formation of dental biofilm is considered to be the main etiology of chronic periodontitis. Bacteria that are often involved in chronic periodontitis are P. gingivalis. Tomatoes (Solanum lycopersicum L.) content with lycopene compounds, flavonoids, and saponins have been shown to inhibit or kill bacterial growth. The aim is to analyze the antibacterial effect of servo tomato ethanol extract against S. mutans and P. gingivalis. Methods: This research was a laboratory experimental one with a posttest only control group design where observed variable diameter of the inhibition zone was produced from ethanolic extract of tomato (Solanum lycopersicum L.) in various concentrations of 3.125, 6.25, 12.5, 25, 50 and 100% chlorhexidine 0.2% as a positive control, negative control of distilled water against S. mutans and P. gingivalis on blood agar media. The method used in this study was the well-diffusion test. Results: The highest inhibitory zone at 100% concentration with a diameter of 32.10 mm was very strong; lowest inhibition at 3.123% was 3.95 mm, weak classification and against P. gingivalis at 3.125%, it was 3.72 mm, weak classification, meanwhile at 100% concentration, it was 9.67 mm, medium classification. The results of the One Way ANOVA statistical test showed a p<0.05 which had a significant effect in inhibiting the growth of S. mutans and P. gingivalis. Conclusions: The ethanolic extract of tomatoes (Solanum lycopersium L.) as the lycopene compounds, flavonoids, and saponins have been shown to have an antibacterial effect in inhibiting bacterial growth of S. mutans and P. gingivalis.

Item Type:	Article
Contributors:	Contribution Contributors NIDN/NIDK Email Author Rahmawati, Dicha Yuliadewi UNSPECIFIED UNSPECIFIED Author Kurniawan, Viola Febi UNSPECIFIED UNSPECIFIED Author Sanjaya, Oei Tirza Cintya UNSPECIFIED UNSPECIFIED Author Sugiaman, Vinna Kurniawati UNSPECIFIED UNSPECIFIED
Uncontrolled Keywords:	tomato ethanol extract (Solanum lycopersicum L.), S. mutans, P. gingivalis, antibacterial
Subjects:	R Medicine > RK Dentistry
Depositing User:	Perpustakaan Maranatha
Date Deposited:	15 Feb 2024 05:59
Last Modified:	15 Feb 2024 05:59
URI:	http://repository.maranatha.edu/id/eprint/32514

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