Widowati, Wahyu and Pryandoko, Didik and Wahyuni, Cintani Dewi and Marthania, Meganita and Kusuma, Hanna Sari Widya and Handayani, Tri and Rizal, Rizal (2021) Antioxidant Properties of Soybean (Glycine max L.) Extract and Isoflavone. In: 2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce), 14-16 July 2021, Medan.
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Abstract
Free radicals caused oxidative stress in the body, which leads to various chronic and degenerative diseases. The negative effects of free radicals can be neutralized by natural antioxidants. Soybean (Glycine max L.) extract contains isoflavones that have several biological activities, including antioxidants. Soybean extract (SE) antioxidant activity was evaluated compared with isoflavones (ISO). The SE was extracted in aquademineral solvent and additional lactose. SE and ISO were subject to various antioxidant activity assay such as 2,2-diphenyl-1-pycrylhydrazyl (DPPH), 2,2’-azinobis- 3-ethylbenzo-thiazoline-6-sulfonicacid (ABTS), H2O2, NO scavenging activities and ferric reducing antioxidant power (FRAP) assay, following standard procedure. As a results, the IC50 of DPPH, ABTS, H2O2, NO, of SE were 246.51; 35.96; 289.41; 39.74 μg/mL respectively. While the IC50 value of isoflavones were 71.37; 23.57; 259.50; 11.59 μg/mL respectively. Furthermore, at the higher concentration (50 μg/mL) of SE and ISO’s FRAP activity were 196.89 and 177.78 μM Fe(II)/μg. Even though the antioxidant activity of SE is lower than isoflavones, SE still has antioxidant potential. Thus, it can be used for supplement candidate.
| Item Type: | Conference or Workshop Item (Paper) |
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| Uncontrolled Keywords: | soybean extract, isoflavones, antioxidant, oxidative stress |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Perpustakaan Maranatha |
| Date Deposited: | 24 Mar 2022 02:41 |
| Last Modified: | 24 Mar 2022 02:41 |
| URI: | http://repository.maranatha.edu/id/eprint/30171 |
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