Potency of Black Soybean (Glycine max (L.) Merr) Extract and Daidzein as Antioxidant and Antihyaluronidase

Asan, Tandiah and I Nyoman , E. Lister and Fachrial, Edy and Amalia, Annisa and Widowati, Wahyu and Samin, Buter and Liena, Liena (2019) Potency of Black Soybean (Glycine max (L.) Merr) Extract and Daidzein as Antioxidant and Antihyaluronidase. Traditional Medicine Journal, 24 (1). ISSN 1410-5918

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Abstract

Black soybean (Glycine max (L.) Merr.) is a plant that is widely planted and consumed in Indonesia. In addition, black soybean has unique content of isoflavones, such as daidzein, which is one of the active compounds that have the effect of fighting free radicals and can inhibit the aging process. The purpose of this study is to analyze the antioxidant potency possessed by black soybean extract (BSE) and daidzeinin inhibiting aging of the skin. The method used is a colorimetric test. The type of antioxidant test used is H2O2 scavenging and inhibiting the activity of the hyaluronidase enzyme for antiaging. BSE has better effectiveness of H2O2 scavenging (IC50: 286.24±11.16 (μg/mL)) than daidzein compound (IC50: 366.16±2.54 (μg/mL)). In the inhibition of hyaluronidase enzyme, the daidzein has more effective activities (IC50: 95.80±3.98 (μg/mL)) compared to BSE (IC50: 152.56±13.98 (μg/mL)). The antioxidant and anti-aging activities possessed by BSE make it possible to be used as a cosmetic ingredient for skin aging therapy. Keywords: Antioxidant, antiaging, Glycine max (L.), Hyaluronidase, H2O2 scavenging

Item Type: Article
Uncontrolled Keywords: Antioxidant, antiaging, Glycine max (L.), Hyaluronidase, H2O2 scavenging
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > 10 School of Medicine
Depositing User: Perpustakaan Maranatha
Date Deposited: 28 Oct 2019 08:25
Last Modified: 28 Oct 2019 08:25
URI: http://repository.maranatha.edu/id/eprint/27078

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