Saliva sebagai Biomarker Potensial Diagnostik Penyakit Rongga Mulut dan Sistemik

Lesmana, Dian and Tjahajawati, Sri and Lubis, Vita Tarawan (2016) Saliva sebagai Biomarker Potensial Diagnostik Penyakit Rongga Mulut dan Sistemik. Dentika: Dental Journal, 19 (2). pp. 160-167. ISSN 1693-671X

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Abstract

Saliva is a biological fluid that is secreted by the major, minor, and other accessories salivary glands. Saliva has a high potential as an indicator that reflects the health of our body. Saliva also plays an important role as a protector, lubricate oral structure with mucin, set a neutral pH trhough the buffer capacity, clean the oral cavity, stimulate wound healing, help the taste buds in the taste of food, facilitate the process of chewing food, form a bolus and make it easier swallowing, and minimize food particles through the activity of the enzyme amylaze and lipase. The use of saliva as a biomarker in diagnosing provide more advantages than the serum and other body fluids due to using non-invasive techniques, cost-efficient, as well as methods for collecting samples for disease screening without the need to train professional personnel. The benefits derived from the saliva as a biomarker are early detection and screening of disease to the development of caries, periodontal disease, tumors and malignancy, hereditary, wound healing, antiimmune disease, infectious diseases, cardiovascular diseases, drug monitoring, forensic, and the psychological influence. At this time, the function of saliva as a diagnostic biomarker is not widely known, therefore the development of salivary further enhance because it can produce functional similarities with the serum and reflect the body's physiological status in the oral cavity and systemic disease.

Item Type: Article
Uncontrolled Keywords: saliva, biomarker, diagnostic, oral and systemic diseases
Subjects: R Medicine > RK Dentistry
Depositing User: Perpustakaan Maranatha
Date Deposited: 14 Aug 2018 05:39
Last Modified: 14 Aug 2018 05:39
URI: http://repository.maranatha.edu/id/eprint/24568

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