Herb for Diabetes

Jasaputra, Diana Krisanti and Suhendra, Adrian and Tjokropranoto, Rita and P., Agistia Lembayung and Darmawan, Laura and Pratama, I Gede Mahatma and T.H.H., Sanggam (2011) Herb for Diabetes. Jurnal Medika Planta, 1 (3). pp. 61-65. ISSN 2086-7514

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Abstract

Introduction: Diabetes mel/itus is one of the disease of aging attributed to chronic fnjlammation is characterized by increasing blood glucose levels, usually with increasingfree radical that can damage pancreas which can be neutralized by antioxidant. Some medicinal plants, have antioxidant effect and have been used empirically by communityfor controlling blood sugar in Diabetes patient Objective: to know hypoglycemic effect of water extract of Andrographis paniculata Nees, Marinda citrifolia Linn, Strobilanthes crispus Bl, Aloe vera L, Persea americana Mill, Orthosiphon spicatus Backer, Phaleria macrocarpa (Schejj) Boeri on mice as diabetes animal model Method: The research design was prospective comparative true experimental using complete random design. The method was diabetic test in alloxan (120 mg/kg bwt, i.v) induced Swiss Webster diabetic mice that given the variation herbs water extract with oral administration and glibenclamide as long as 7 days Data measured are blood glucose levels!BGL (mg/ dL) after alloxan induced and after the treatment. Percentage in lowering blood glucose levels data analyzed used ANO VAon ranks continued by Dunnett 'sMultiple Comparisons, a. = 0.05. Result: There is lowering BGL after treatment with Andrographis paniculata Nees (29.33%), Marinda citrifolia Linn (15.50%), Strobilanthes crispus Bl (12.50%), Aloe vera L (40.46%), Persea americana Mill (44.44%), Orhtosiphon spicatus Backer (43.34%), Phaleria macrocarpa (Schejj) Boe.fl (34.51%) that is significantly difference compared to negative control (-1.58%) (p<0,05). Conclusion: Andrographis paniculata Nees, Marinda citrifolia Linn, Strobilanthes crispus Bl, Aloe vera L, Persea americana Mill, Orthosiphon spicatus Backer, Phaleria macrocarpa (Schejj) Boeri have hypoglycemic effect on al/oxan induced Swiss Webster mice.

Item Type: Article
Uncontrolled Keywords: hypoglycemic effect of some medicinal plant, alloxan
Subjects: R Medicine > R Medicine (General)
Depositing User: Perpustakaan Maranatha
Date Deposited: 16 Apr 2018 08:29
Last Modified: 16 Apr 2018 08:29
URI: http://repository.maranatha.edu/id/eprint/24345

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