Phytochemical Features of Moringa oleifera Leaves as Anticancer A Review Article

Edwinanto, Ludovicus and Septiadi, Endry and Nurfazriah, Latifah R. and Anastasya, Karina S. and Pranata, Natallia (2018) Phytochemical Features of Moringa oleifera Leaves as Anticancer A Review Article. Journal of Medicine and Health, 2 (1). pp. 680-688. ISSN 2442-5257

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Cancer is a disease that can threaten human life. Various methods of cancer therapy have been widely practiced, one of which is chemotherapy. But the cost used for the therapy is also very expensive. This difficulty led many researchers to conduct research to find active compounds from natural materials. Moringa leaf (Moringa oleifera) has cytotoxic activity, because it contains a lot of flavonoids. Flavonoids are polyphenol compounds produced from secondary metabolism in plants. The most flavonoids that are anticancer active substances in the Moringa leaf are quercetin, kaempferol and myricetin. Cytotoxic activity because these active substances can induce apoptosis through intrinsic pathways by inhibition of mitogenactivated protein kinase (MAPK), extracellular-signal-regulated kinase 1/2 (ERK 1/2), c-Jun Nterminal protein kinase 1 (JNK), and protein kinase C (PKC).

Item Type: Article
Uncontrolled Keywords: Moringa leaf, quersetin; kaempferol; myricetin; anticancer
Subjects: R Medicine > R Medicine (General)
Depositing User: Perpustakaan Maranatha
Date Deposited: 02 Mar 2018 07:33
Last Modified: 02 Mar 2018 07:43

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