Azaria, Cherry and Achadiyani, Achadiyani and Farenia, Reni (2017) Topical Effect of Pinneaple (Ananas comosus) Juice in Combustio Healing Process Measured by Granulation Process, Reepitelialisation and Angiogenesis. Journal of Medicine and Health, 1 (5). pp. 432-444. ISSN 2442-5257
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Abstract
Skin protects the body from various trauma, such as high temperature trauma known as combustio. Pineapple (Ananas comosus) contains lots of substances such as bromelain, antioxidants, and zinc shown to accelerated healing process in previous experiments. Aim of this research was to analize the effect of topical pinneaple juice application in combustio healing process. The method was true experimental laboratory. Wistar rats’ back skin were induced by 100oC iron plat untill 2nd degree combustio occured, then divided into two groups (n=20). The treatment group were given topical application of pinneaple juice, then the healing process were observed macroscopically and microscopically on day 0, 3, 7, and 14. The result showed better wound healing in treatment group on day 14. MANOVA test showed topical application of pinneaple juice accelerated healing process (p=0.001). Treatment group showed better histological structure changes, as seen from better granulation tissue formed (p=0.003) and reepithelization (p=0,000), but not from angiogenesis (p=0.733). Conclusion, topical application of pinneaple (Ananas comosus) juice accelerated healing process in 2nd grade of combustio animal model measured by granulation maturation process and reepithelization process, but has no effect on angiogenesis.
| Item Type: | Article |
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| Uncontrolled Keywords: | Ananas comosus juice, 2nd degree combustio, granulation tissue, reepitelisation, angiogenesis. |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Perpustakaan Maranatha |
| Date Deposited: | 06 Mar 2017 08:24 |
| Last Modified: | 06 Mar 2017 08:24 |
| URI: | http://repository.maranatha.edu/id/eprint/21819 |
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