Rahardja, Fanny and Tjokropranoto, Rita and Widowati, Wahyu and Lusiana, Siska and Suhendra, Adrian and Tjahjani, Susy and Budiman, Iwan and Maesaroh, Maesaroh and Fauziah, Nurul (2015) Phytochemical Assay, Potential of Antimalarial and Antioxidant activities of Green Tea Extract and Its Fraction. Biomedical Engineering, 1 (1). pp. 1-7. ISSN 2356-2471
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Abstract
Objective : The research objective was to evaluate the phytochemical compounds, the antioxidant and anti-malarial activity of green tea extract and its fraction. Methods : The antioxidant activity were measured by 1,1-diphenyl-2-picryl-hydrazyl (DPPH) scavenging activity used in vitro laboratories prospective experimental design and completely randomized design, using ethanol extract, hexane, ethyl acetate, butanol fraction, and water fraction of green tea in 7 levels of concentration compared to epicatechin (EC). The data were analyzed using linear regression analysis, and were continued by determined Inhibitory Concentration50 (IC50). The anti-malarial activity of green tea fractions were compared to artemisinin. The data were analyzed using probit analysis, and were continued by determined IC50 . Result: The results showed that the highest antioxidant activity (IC50) was the fraction of ethyl acetate 2,184 μg/ml. The anti-malarial activity IC50of water and ethyl acetate fraction, ethanol extract and butanol fraction were 0,000090 μg/mL,0,003 μg/mL, 0,006 μg/mL, 0,011 μg/ml respectively.
| Item Type: | Article |
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| Uncontrolled Keywords: | Extract and fractions of green tea have potential anti-malarial and antioxidant properties. |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Perpustakaan Maranatha |
| Date Deposited: | 17 Sep 2015 07:22 |
| Last Modified: | 17 Sep 2015 07:22 |
| URI: | http://repository.maranatha.edu/id/eprint/15161 |
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