Inflammation, Immunity, and Cancer: The Role of Transcription Factors NF-kB and STAT3

Khie Khiong, - and Adhika, Oeij Anindita and Chakravitha, Melisa (2010) Inflammation, Immunity, and Cancer: The Role of Transcription Factors NF-kB and STAT3. Majalah Kedokteran Indonesia, 60 (8). pp. 369-373. ISSN 0377-1121

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Abstract

A link between inflammation and cancer has long been suspected. Recent studies have identified the role of transcription factors nuclear factor-kB (NF-kB) and signal transducer and activator of transcription 3 (STAT3) in inflammation-induced tumor. In this review, we focus on the role of NF-kB and STAT3 in regulating functions of cancer cells and surrounding non-tumorigenic cells to create a tumor microenvironment that enhance tumor promotion and progression.

Item Type: Article
Uncontrolled Keywords: inflammation, cancer, NF-kB, STAT3
Subjects: R Medicine > R Medicine (General)
Depositing User: Perpustakaan Maranatha
Date Deposited: 17 Jun 2015 04:30
Last Modified: 17 Jun 2015 04:42
URI: http://repository.maranatha.edu/id/eprint/13201

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